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Index > Protein center > KLK1(Gene name) > Human
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  • KLK1 (Gene name),
  • Kallikrein-1 (Protein name ),  KLK1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    KLK1;
    Protein name:
    Kallikrein-1;
    Alternative:
    Tissue kallikrein;Kidney/pancreas/salivary gland kallikrein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    262
    Sequence:
    50:
    MWFLVLCLAL | SLGGTGAAPP | IQSRIVGGWE | CEQHSQPWQA | ALYHFSTFQC | 
    100:
    GGILVHRQWV | LTAAHCISDN | YQLWLGRHNL | FDDENTAQFV | HVSESFPHPG | 
    150:
    FNMSLLENHT | RQADEDYSHD | LMLLRLTEPA | DTITDAVKVV | ELPTEEPEVG | 
    200:
    STCLASGWGS | IEPENFSFPD | DLQCVDLKIL | PNDECKKAHV | QKVTDFMLCV | 
    250:
    GHLEGGKDTC | VGDSGGPLMC | DGVLQGVTSW | GYVPCGTPNK | PSVAVRVLSY | 
    262:
    VKWIEDTIAE | NS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    String:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Kallikrein-1
    Cat.:
    E0967m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Kallikrein-1
    Cat.:
    E0967h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Kallikrein-1
    Cat.:
    U0967h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Kallikrein-1
    Cat.:
    U0967m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Kallikrein-1
    Cat.:
    P0967Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Kallikrein-1
    Cat.:
    P0967Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Kallikrein-1
    Monoclonal Antibody for Human Kallikrein-1
    Protein for Human Kallikrein-1
    Protein for Human Kallikrein-1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Nucleotide sequence of cloned cDNA for human pancreatic kallikrein."
      Fukushima D. , Kitamura N. , Nakanishi S.
      Biochemistry24:8037-8043(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS GLN-145 AND GLU-186
      tissue: Pancreas.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLN-145
      tissue: Kidney.
    3. 3.
      "Cloning and expression of human salivary-gland kallikrein in Escherichia coli."
      Angermann A. , Bergmann C. , Appelhans H.
      Biochem. J.262:787-793(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Salivary gland.
    4. 4.
      "Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues."
      Chen L.-M. , Murray S.R. , Chai K.X. , Chao L. , Chao J.
      Braz. J. Med. Biol. Res.27:1829-1838(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);ALTERNATIVE SPLICING;TISSUE SPECIFICITY
    5. 5.
      "Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4."
      Yousef G.M. , Chang A. , Scorilas A. , Diamandis E.P.
      Biochem. Biophys. Res. Commun.276:125-133(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region."
      Gan L. , Lee I. , Smith R. , Argonza-Barrett R. , Lei H. , McCuaig J. , Moss P. , Paeper B. , Wang K.
      Gene257:119-130(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "Kallikrein cDNA from the pancreas of a Chinese patient."
      Li T. , Du G. , Dai Y.
      Submitted (2004-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS GLN-145 AND GLU-186
    8. 8.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLN-145
    9. 9.
      SeattleSNPs variation discovery resource
      Submitted (2002-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLN-145
    10. 10.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    11. 11.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLN-145
      tissue: Pancreas.
    12. 12.
      "Human kidney kallikrein: cDNA cloning and sequence analysis."
      Baker A.R. , Shine J.
      DNA4:445-450(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 18-262 (ISOFORM 1);VARIANTS GLN-145 AND GLU-186
      tissue: Kidney.
    13. 13.
      "Human urinary kallikrein -- amino acid sequence and carbohydrate attachment sites."
      Kellermann J. , Lottspeich F. , Geiger R. , Deutzmann R.
      Protein Seq. Data Anal.1:177-182(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-262 (ISOFORM 1);GLYCOSYLATION AT SER-93; ASN-102; SER-104; ASN-108; ASN-165 AND SER-167
      tissue: Urine.
    14. 14.
      "Human urinary kallikrein. Complete amino acid sequence and sites of glycosylation."
      Lu H.S. , Lin F.-K. , Chao L. , Chao J.
      Int. J. Pept. Protein Res.33:237-249(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-262 (ISOFORM 1)
      tissue: Urine.
    15. 15.
      "N-terminal amino acid sequence of human urinary kallikrein homology with other serine proteases."
      Lottspeich F. , Geiger R. , Henschen A. , Kutzbach C.
      Hoppe-Seyler's Z. Physiol. Chem.360:1947-1950(1979) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-55 (ISOFORM 1)
      tissue: Urine.
    16. 16.
      "N-terminal amino acid sequence of human urinary prokallikrein."
      Takahashi S. , Irie A. , Katayama Y. , Ito K. , Miyake Y.
      J. Biochem.99:989-992(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-47 (ISOFORM 1)
      tissue: Urine.
    17. 17.
      "1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding."
      Laxmikanthan G. , Blaber S.I. , Bernett M.J. , Scarisbrick I.A. , Juliano M.A. , Blaber M.
      Proteins58:802-814(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 25-262;GLYCOSYLATION AT ASN-108;DISULFIDE BONDS
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